Richard Axel, M.D., HHSC 1014, Ext. 5-6915
Defining the logic of olfactory perception; how individual sensory neurons express a specific receptor and how the brain distinguishes which receptors have been activated.
Kathryn L. Calame, Ph.D., HHSC 1201, Ext. 5-3504
Transcriptional regulatory cascades required for terminal differentiation of B lymphocytes and monocyte/macrophages; transformation of preB cells by the v-Abl tyrosine kinase.
Stephen P. Goff, Ph.D., HHSC 1310, Ext. 5-3794
Retroviral replication; tyrosine kinase oncogenes.
Max E. Gottesman, M.D., Ph.D., HHSC 914, Ext. 5-6900
Regulation of transcription termination in E. coli and bacteriophage; role of cAMP in cell cycle progression and signal transduction in eukaryotes; vitamin A metabolism in the mouse.
Eric Gouaux, Ph.D., BB 513, Ext. 5-4475
Structure, function and chemistry of membrane proteins; X-ray crystallographic, molecular genetic and biochemical approaches.
Eric C. Greene, Ph.D., BB 536, Ext. 2-2944
Our lab utilizes total internal reflection fluourescence microscopy (TIRFM) to study the molecular machinery involved in the recombination and repair of damaged DNA. Using TIRFM to directly observe single reactions in real-time we can analyze the molecular mechanisms our cells use to fix damaged DNA with a degree of sensitivity not previously possible.
Iva Greenwald, Ph.D., HHSC 720, Ext. 5-6928
Cell-cell interactions, signal transduction, and cell fate choice; genetic and molecular studies of C. elegans development.
Wayne A. Hendrickson, Ph.D., BB 203, Ext. 5-3456
Structural biology of macromolecules; differentiation and computational methods.
David Hirsh, Ph.D., 305 Low Library, MC4310, Tel. (212) 854-1696
Molecular genetics of endocytosis in C. elegans; role of cytokines in the mammalian inflammatory and immune responses.
Oliver Hobert, Ph.D., HHSC 726A, Ext. 5-0063
Genetic programs that control neural development in C. elegans.
Barry Honig, Ph.D., BB 221, Ext. 5-7970
Computational biology, bioinformatics, prediction of protein structure and function.
Thomas M. Jessell, Ph.D., HHSC 1013, Ext. 5-1531
Molecular mechanisms of neuronal differentiation, axon guidance and cell recognition in vertebrate development.
Eric Kandel, M.D., P.I. Annex 664, Ext. 5-4143
Cell and molecular mechanisms of associative and non-associative learning in invertebrates and vertebrates.
Arthur Karlin, Ph.D., P&S 11-401, Ext. 5-5778
Molecular mechanisms of receptor function.
Richard S. Mann, Ph.D., HHSC 1104A, Ext. 5-7731
Control of pattern formation by homeotic genes and their downstream targets in Drosophila.
Arthur G. Palmer, III, Ph.D., (Acting Chair) P&S 5-424, Ext. 5-3669, Lab BB 507, 5-8675
Structure, function and dynamics of proteins; fluctuation in chemical and biological systems and nuclear magnetic resonance; and fluorescence spectroscopies.
Burkhard Rost, Ph.D., BB 217, Ext. 5-3773
Bioinformatics. Goals: sequence analysis, prediction of protein structure and function. Means: statistics and artificial intelligence.
Lawrence Shapiro, Ph.D., Eye Inst. 902A, Tel. 342-6029
Structural information obtained from X-ray crystallography to direct biochemical studies of biological problems, particularly involving neuronal cell adhesion and neural patterning.