Download Handbook of Neurochemistry and Molecular Neurobiology Free PDF Books - Free PDF

Download Handbook of Neurochemistry and Molecular Neurobiology Free PDF Books

Springer Science & Business Media

English - 492 pages - ISBN-10: 0387303588 - ISBN-13: 9780387303581

2/5 by 99 votes


Neuroimmunology is one of the most rapidly developing branches of Neurobiology, prompted by novel neurochemical, neuroendocrinological and neurophysiological investigations of the central and peripheral nervous system including neuro-endocrine systems. Neuroimmunology can be considered an interdisciplinary science that covers relevant aspects of how the peripheral immune system can influence brain physiology and elicit neuro-endocrine immuno-regulatory responses and also how local interactions between immune and neuronal mediators of the brain influence the occurrence and course of neuropathologic diseases. That explains the reason why we have in this volume chapters that focus on immune-neuro-endocrine interactions underlying the control and regulation of processes involved in both immune and brain physiology and in the pathogenesis of different nervous diseases. Among such diseases are: schizophrenia, HIV, associated dementia, rheumatoid arthritis, several experimental pathologies, multiple sclerosis, autoimmune encephalomyelitis, Theilers virus infection, nervous system demyelination diseases, the primary degenerative disorders such as Alzheimer’s and Parkinson’s as well as brain injuries resulting from stroke and trauma, the neuroimmunology of gene therapy, amyotrophic lateral sclerosis, prion disease and all theoretical questions covering these pathologies. All of the above mentioned involve autoimmune processes. It is difficult, indeed, to imagine fundamental neurobiological processes, autoimmune, neuroendocrine and infectious diseases, where immune factors are not of prime importance. The elucidation of the intimate molecular-biological problems of immunopathologies requires deep knowledge of the intricate connection between immunomodulators, immune competent cells of blood, brain, and other organs. This volume contains data on multiple immunomodulators, many of which are also the products of hypothalamic brain cell neurosecretion. Interleukins (IL-1a, IL-1ß, IL-2, IL-4, IL-6, TNFa), immunophylin and ubiquitin as well as proline rich peptides, comprised of 10-15 amino acids are being produced in N. Supraopticus and N. Paraventricularis and then secreted into neurohypophysis. Along the neurosecretion of the mentioned cytokines, there are other immunomodulators, the primary structure of which had been completely deciphered such as: Immunophyllins, intracellular receptors of immunosuppressors FK506, cyclosporine A., rapamicin. They are peptidyl-prolyl-cis-trans-isomerases. There are novel immunological hypothalamic factors such as ubiquitin, macrophage migration inhibitory factor (MIF), as well as Thymosin ß 4(1-39). This data allowed us to propose the concept of neuroendocrine immune system of the brain.

468x60

Reviews

64x64

Ivan Johnson

Could not let the book down Sure not a literary master piece, but as one of the reviewers stated, it will keep you turning the pages.

Michelle Anderson

Nice It has a nice story about how to always let go the past and fall in love.

Ben Anderson

Good book

300x250

Recent Books

La sémantique du prédicat en mwotlap, Vanuatu
La sémantique du prédicat en mwotlap, Vanuatu
Alexandre François
Langue melanesienne de tradition orale, le mwotlap (motlav) appartient a la branche oceanienne de la famille austronesienne; il est actuellement...
Handbook of Neurochemistry and Molecular Neurobiology
Handbook of Neurochemistry and Molecular Neurobiology
Abel Lajtha
Neuroimmunology is one of the most rapidly developing branches of Neurobiology, prompted by novel neurochemical, neuroendocrinological and...
The Storm Before the Storm
The Storm Before the Storm
Mike Duncan
NEW YORK TIMES BESTSELLER The creator of the award-winning podcast series The History of Rome and Revolutions brings to life the bloody battles,...
Lonely Planet Tokyo
Lonely Planet Tokyo
Lonely Planet
Lonely Planet: The world's leading travel guide publisher Lonely Planet Tokyo is your passport to the most relevant, up-to-date advice on what to see...